Effect of Quorum Quenching Lactonase in Clinical Isolates of Pseudomonas aeruginosa and Comparison with Quorum Sensing Inhibitors
نویسندگان
چکیده
منابع مشابه
Effect of Quorum Quenching Lactonase in Clinical Isolates of Pseudomonas aeruginosa and Comparison with Quorum Sensing Inhibitors
Pseudomonas aeruginosa is a Gram negative pathogenic bacterium involved in many human infections including otitis, keratitis, pneumonia, and diabetic foot ulcers. P. aeruginosa uses a communication system, referred to as quorum sensing (QS), to adopt a group behavior by synchronizing the expression of certain genes. Among the regulated traits, secretion of proteases or siderophores, motility an...
متن کاملCoexistence of quorum-quenching and quorum-sensing in tropical marine Pseudomonas aeruginosa strain MW3A.
A chemically defined medium called KGm medium was used to isolate from a sample of sea water a bacterial strain, MW3A, capable of using N-3-oxohexanoyl-L: -homoserine lactone as the sole carbon source. MW3A was clustered closely to Pseudomonas aeruginosa by 16S ribosomal DNA sequence analysis. It degraded both N-acylhomoserine lactones (AHLs) with a 3-oxo group substitution and, less preferably...
متن کاملSynergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P. aeruginosa Quorum Sensing
1 School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551 6 2 Nanyang Environment and Water Research Institute (NEWRI), Interdisciplinary Graduate School, 7 Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 8 3 NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, 9 Singapore 636921 10 ...
متن کاملDraft Genome Sequence of Quorum-Sensing and Quorum-Quenching Pseudomonas aeruginosa Strain MW3a
Pseudomonas aeruginosa has a broad range of habitation, from aquatic environments to human lungs. The coexistence of quorum-sensing and quorum-quenching activities occurs in P. aeruginosa strain MW3a. In this work, we present the draft genome sequence of P. aeruginosa MW3a, an interesting bacterium isolated from a marine environment.
متن کاملQuorum-Sensing Regulator LasR in Pseudomonas aeruginosa
± Current Address: Department of Microbiology, University of Washington School of 21 Medicine, 1959 NE Pacific St., Room K-360, Seattle, WA 98195-7242. 22 23 ね Current address: Department of Molecular, Cellular and Developmental Biology, 24 219 Prospect St., Yale University, New Haven, CT 06471 25 26 * Corresponding author. Mailing address: Department of Molecular, Cellular and 27 Developmental...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2017
ISSN: 1664-302X
DOI: 10.3389/fmicb.2017.00227